xCELLigence RTCA eSight analyzer

The xCELLigence RTCA eSight is an advanced tool for comprehensive, real-time, and live cell analysis. Combining label-free xCELLigence RTCA technology with real-time live cell imaging in three fluorescence channels – red, green, and blue, this revolutionary analyzer allows for an insightful study into cell viability behavior, and biological processes. By merging impedance-based and image-based measurements, the eSight system presents a deeper understanding of cell health and functionality.

Key Advantages

• Informative Data: Delivers physiologically relevant data by monitoring cell health, strength of adhesion, changes in morphology, proliferation, and cytolysis in primary cell cultures or standard tissue culture cell lines.
• Flexible Live Cell Imaging: Offers brightfield capabilities, three fluorescence channels, compatibility with various well plate formats, and user-defined schedules.
• Continuous Analysis: Provides a constant readout of cell number, proliferation rate, cell size/shape, and cell-substrate attachment quality.

Applications

• Immune Cell Killing Assays: Simulate in vivo activity of immune cell killing potency.
• Viral Cytopathic Effect Assays: Facilitates anti-viral therapy or vaccine development by measuring viral cytopathic effects in real time.
• Cytotoxicity Assays: Monitor cytotoxic effects of drugs or compounds with real-time analysis of cell proliferation, cell size or morphology, and cell-substrate attachment quality.
• Apoptosis and Proliferation Assays: Measure real-time cell health and detect early and late apoptotic events in High-throughput assays.
• Phagocytosis: Analyze immune system processes by tracking the entire process in real time through imaging, screen for pathway modulators, and discover potential therapeutic interventions.