BioFlo 510 – Industrial Fermenter

The BioFlo 510, a product of the Eppendorf industrial fermentor series, is a compact Sterilizable-In-Place (SIP) fermentation system engineered to cater to the needs of research and production. Tailored to function effectively in pilot to small-scale production processes, its modular design provides scientists with the flexibility to configure the system to precisely fit their needs. Boasting a wide variety of standard options, the BioFlo 510 can adapt to most process requirements. It integrates a diverse range of utilities including various Total Mass Flow Controllers (TMFCs) for gas flow, a selection of impellers suitable for various cell lines, sensors for effective process monitoring, multiple validation packages, utility regulator and pre-filter kits, and additional options such as sprayballs for clean-in-place of vessel and mobile table.

Key Advantages

• Reactor Process Control (RPC) software for full control of the fermentor systems
• Stainless steel electropolished vessels with 2:1 aspect ratios and a working volume of 32.0 L
• Integrated load cell for real-time vessel volume monitoring
• Incorporation of 3-fixed speed peristaltic pumps for additions, harvest, and pH control
• Choice between benchtop or mobile setup
• Furnished with Rushton-type impellers with the option for pitched-blade and marine blades
• Industrial-grade touchscreen interface for user-friendly operations

Applications

• Laboratory- and pilot-scale fermentation of aerobic and anaerobic bacteria, yeasts, and fungi
• Laboratory- and pilot-scale cell culture of mammalian, insect, and human cell lines
• Specialized uses include stem cell culture, vaccine production, monoclonal antibody production, and biofuel or biopolymer production
• Suitable for batch, fed-batch, and continuous/perfusion processes